Carcinogenetic initiation contributed by EpCAM+ cancer cells in orthotopic HCC models of immunocompetent and athymic mice

Objective: The expression of the epithelial cell adhesion molecule (EpCAM) is correlated with a poor prognosis, and treatment failure early tumor recurrence of hepatocellular carcinoma (HCC) patients. The tumor microenvironment determine the fate of tumor cancer stem cell-start (CSC); However, very limited studies that seek to evaluate CSC tumorigenesis in the liver microenvironment. Here, we have systematically investigated the role of EpCAM + cancer cells in tumor initiation in an orthotopic model of HCC.


Result: control mice and mice with bland steatosis failed to develop tumors. In rats with steatohepatitis, EpCAM + CSC has demonstrated a significant improvement in terms of the ability of tumor initiation and growth, as compared to non-CSC EpCAM- inoculation (p <0.005). For Hep3B inoculation, high-EpCAM group has demonstrated tumor growth was significantly higher compared with EpCAM-Low (p <0.005). For HepG2 inoculation, both high EpCAM and EpCAM-Low group confirmed the same tumor incidence and growth.


Methods: Diet-induced compromised microenvironments fatty liver was established to mimic the clinical and patient non-alcoholic steatohepatitis (NASH) and the ability of tumorigenic cells Hepa1-6 evaluated. CSC is enriched by the cultural round and labeled with copGFP for EpCAM + CSC and with mCherry for non-CSC. FACS-sorted cells were inoculated into the left lobe of the liver, and the tumor growth was monitored by high frequency ultrasound. The Hep3B and HepG2 cell subpopulations in terms of EpCAM-low and high EpCAM was evaluated in an orthotopic model of athymic mice.


Conclusion: NASH micro EpCAM + CSC began promoting tumorigenesis in a mouse model of immunocompetent. EpCAM showed differential expression of different tumor biology in athymic mouse model.

 Carcinogenetic initiation contributed by EpCAM+ cancer cells in orthotopic HCC models of immunocompetent and athymic mice
Carcinogenetic initiation contributed by EpCAM+ cancer cells in orthotopic HCC models of immunocompetent and athymic mice

Multimodal imaging of stem cell-derived bulge of hair follicles in a mouse model of traumatic brain injury.

traumatic brain injury (TBI) is a devastating event therapy is currently limited. Stem cell transplantation may lead to recovery of function through different mechanisms, such as the replacement of cells through differentiation, angiogenesis stimulation and support for micro environment. Adult hair follicle bulge-derived stem cells (HFBSCs) has a capacity of neuronal differentiation, it is easy to harvest and relatively immune-privileged, which makes them potential candidates for autologous stem cell-based therapies.

In this study, we apply the in vivo multimodal techniques of optical and magnetic resonance imaging to investigate the behavior of HFBSCs mouse in a mouse model of TBI. HFBSCs stated Luc2 and copGFP and examined for their differentiation capacity in vitro. Furthermore, HFBSCs transduced, loaded with ferumoxytol, transplanted next TBI lesions (cortical region) in nude mice, two days after the injury. Brains were fixed for immunohistochemistry 58 days after transplantation. Luc2- and copGFP-express, HFBSCs ferumoxytol-loaded show sufficient differentiation potential of neurons in the brain lesions revealed vitro.

Bioluminescence HFBSCs survival and magnetic resonance imaging identified their localization in the field of transplantation. Immunohistochemistry showed that the transplanted cells stained for nestin and Neurofilament protein (NF-Pan). Cells also expressed laminin and fibronectin extracellular matrix but the mass was not detected.

pCDH-MSCV-MCS-EF1-GFP cDNA Cloning and Expression Vector

CD711B-1 10 ug
EUR 572

pCDH-MSCV-MCS-EF1-Puro cDNA Cloning and Expression Vector

CD710B-1 10 ug
EUR 572

pCDH-MSCV-MCS-IRES-GFP cDNA Cloning and Expression Vector

CD731B-1 10 ug
EUR 590

pCDH-CMV-MCS-EF1-copGFP cDNA Cloning and Expression Vector

CD511B-1 10 ug
EUR 572

pCDH-MSCV-MCS-EF1-GFP+Puro cDNA Cloning and Expression Vector

CD713B-1 10 ug
EUR 572

pCDH-EF1-MCS-(PGK-GFP-T2A-Puro) Cloning and Expression Vector

CD813A-1 10 ug
EUR 579

pCDH-EF1-MCS-T2A-RFP (PGK-Puro) Cloning and Expression Vector

CD822A-1 10 ug
EUR 579

pCDH-EF1-MCS-T2A-GFP (PGK-Puro) Cloning and Expression Vector

CD823A-1 10 ug
EUR 579

pCDH-CMV-MCS cDNA Cloning and Expression Vector

CD500B-1 10 ug
EUR 483

pCDH-EF1-MCS cDNA Cloning and Expression Vector

CD502A-1 10 ug
EUR 483

pCDH-EF1-MCS-T2A-Puro cDNA Cloning and Expression Vector 10 µg

CD527A-1 10 ug
EUR 590

pCDH-EF1-MCS-(PGK-GFP) Cloning and Expression Vector

CD811A-1 10 ug
EUR 579

pCDH-EF1-MCS-(PGK-Puro) Cloning and Expression Vector

CD810A-1 10 ug
EUR 579

pCDH-EF1-MCS-BGH-PGK-GFP-T2A-Puro cDNA Cloning and Expression Vector

CD550A-1 10 ug
EUR 563

pCDH- EF1- MCS- T2A- copGFP

PVT2336 2 ug
EUR 390

pCDH-CMV-MCS-EF1-RFP cDNA Cloning and Expression Vector

CD512B-1 10 ug
EUR 572

pCDH-CMV-MCS-EF1-Neo cDNA Cloning and Expression Vector

CD514B-1 10 ug
EUR 572

pCDH-CMV-MCS-EF1-Puro cDNA Cloning and Expression Vector

CD510B-1 10 ug
EUR 572

pCDH-EF1-MCS-IRES-GFP cDNA Cloning and Expression Vector

CD530A-2 10 ug
EUR 590

pCDH-EF1-MCS-IRES-RFP cDNA Cloning and Expression Vector

CD531A-2 10 ug
EUR 590

pCDH-EF1-MCS-IRES-Neo cDNA Cloning and Expression Vector

CD533A-2 10 ug
EUR 590

pCDH-UbC-MCS-IRES-GFP cDNA Cloning and Expression Vector

CD630A-1 10 ug
EUR 590

pCDH-CMV-MCS-EF1-Hygro cDNA Cloning and Expression Vector

CD515B-1 10 ug
EUR 572

pCDH-EF1-MCS-IRES-Puro cDNA Cloning and Expression Vector

CD532A-2 10 ug
EUR 590

pCDH-UbC-MCS-EF1-Hygro cDNA Cloning and Expression Vector

CD615B-1 10 ug
EUR 572

pCDH-CMV-MCS-EF1-GreenPuro cDNA Cloning and Expression Vector

CD513B-1 10 ug
EUR 572

pCDH-CMV-MCS-EF1-RFP+Puro cDNA Cloning and Expression Vector

CD516B-2 10 ug
EUR 572

pAAVK-EF1α -MCS-T2A-EGFP AAVanced Cloning and Expression Vector

AAV526A-1 10 ug
EUR 614

pAAVK-EF1α -MCS-T2A-Puro AAVanced Cloning and Expression Vector

AAV527A-1 10 ug
EUR 614

pAAVK-EF1α –MCS-T2A-mRFP AAVanced Cloning and Expression Vector

AAV528A-1 10 ug
EUR 614

pCDH-CMV-MCS2 cDNA Cloning and Expression Vector

CD501A-1 10 ug
EUR 483

PB-MSCV-MCS-EF1-GreenPuro cDNA Cloning and Expression Vector

PB713B-1 10 ug
EUR 638

pCDH- CMV- MCS- EF1- CopGFP- T2A- Puro

PVT2333 2 ug
EUR 390

XStamp cloning and expression lentivector MSCV-Leader-MCS-C1C2-EF1-Puro

XSTP710PA-1 10 ug
EUR 730

pAAVK-EF1α -MCS AAVanced Cloning and Expression Vector

AAV502A-1 10 ug
EUR 614

pCDF1-MCS2-EF1-copGFP cDNA Cloning and Expression Vector

CD111B-1 10 ug
EUR 572

pSIH1-H1-copGFP shRNA Cloning and Expression Vector

SI501A-1 10 ug
EUR 507

PB-CMV-MCS-EF1-GFP cDNA cloning and expression vector

PB511B-1 10 ug
EUR 638

PB-CMV-MCS-EF1-RFP cDNA cloning and expression vector

PB512B-1 10 ug
EUR 638

PB-CMV-MCS-EF1-Puro cDNA cloning and expression vector

PB510B-1 10 ug
EUR 638

PB-EF1-MCS-IRES-GFP cDNA cloning and expression vector

PB530A-2 10 ug
EUR 638

PB-EF1-MCS-IRES-RFP cDNA Cloning and Expression Vector

PB531A-2 10 ug
EUR 638

PB-EF1-MCS-IRES-Neo cDNA cloning and expression vector

PB533A-2 10 ug
EUR 638

PB-CMV-MCS-EF1-RedPuro cDNA Cloning and Expression Vector

PB514B-2 10 ug
EUR 638

PB-CMV-GreenPuro-H1-MCS shRNA cloning and expression vector

PBSI505A-1 10 ug
EUR 638

PB-EF1-GreenPuro-H1-MCS shRNA cloning and expression vector

PBSI506A-1 10 ug
EUR 638

PB-CMV-MCS-EF1-GreenPuro cDNA cloning and expression vector

PB513B-1 10 ug
EUR 638

pCDF1-MCS1 cDNA Cloning and Expression Vector

CD100A-1 10 ug
EUR 483

pCDH- CMV- MCS- EF1- copGFP Plasmid

PVT2334 2 ug
EUR 390

PB-CuO-CMV-MCS-EF1α-CymR-Puro Inducible cDNA Cloning and Expression Vector

PBQM800A-1 10 µg
EUR 921

pSIH1-H1-Puro shRNA Cloning and Expression Vector

SI500A-1 10 ug
EUR 507

pSIH1-H1-H2Kk shRNA Cloning and Expression Vector

SI502A-1 10 ug
EUR 507

PB-Cuo-MCS-IRES-GFP-EF1-CymR-Puro Inducible cDNA Cloning and Expression Vector

PBQM812A-1 10 ug
EUR 1023

Cumate-Inducible (CuO) EEV cloning and expression vector

EEV610A-1 10 ug
EUR 614

Constitutive (CAGs promoter) EEV cloning and expression vector

EEV600A-1 10 ug
EUR 614

pAAVK-EF1α-MCS1-CMV-MCS2 AAVanced Cloning and Expression Vector

AAV503A-1 10 ug
EUR 614

pAAVK-EF1α-MCS1-CMV-EGFP AAVanced Cloning and Expression Vector

AAV536A-1 10 ug
EUR 614

pAAVK-EF1α-MCS1-CMV-Puro AAVanced Cloning and Expression Vector

AAV537A-1 10 ug
EUR 614

pAAVK-EF1α-MCS1-CMV-mRFP AAVanced Cloning and Expression Vector

AAV538A-1 10 ug
EUR 614

ProFold-C1. Baculovirus chaperone vector for expression of cytoplasmic and nuclear proteins.

A2 25 ul
EUR 830
Description: Protein expression

ProFold-C2. Baculovirus chaperone vector for expression of cytoplasmic and nuclear proteins.

A3 25 ul
EUR 830
Description: Protein expression

ProFold-ER1. Baculovirus chaperone vector for expression of secreted and membrane proteins.

A4 25 ul
EUR 830
Description: Protein expression

ER1 Kit. Baculovirus chaperone vectors for expression of secreted and membrane proteins.

K23 1 Kit
EUR 995
Description: Protein expression

pLenti-SFFV-MCS-EF1-copGFP Lentiviral Expression Vector

LV460 10 µg
EUR 416.5

ER1-bee Kit. Baculovirus chaperone vectors for expression of secreted and membrane proteins.

K24 1 Kit
EUR 995
Description: Protein expression

pCDF1-MCS2-EF1-Puro cDNA Cloning and Expression Lentivector

CD110B-1 10 ug
EUR 572

PB-Cuo-shMCS-IRES-GFP-EF1-CymR-Puro Inducible shRNA Cloning and Expression Vector

PBQMSH812A-1 10 ug
EUR 1023

pAcAB3. Baculovirus plasmid vector for expression of up to 3 proteins.

B2 50 ul
EUR 420
Description: Protein expression

baculoCOMPLETE protein expression kit

400100 5 reactions
EUR 874.2

ProFold-PDI. Baculovirus chaperone vector for expression of cysteine-rich proteins.

A7 25 ul
EUR 830
Description: Protein expression

pLenti-MCS-EF1-GFP-T2A-puro Lentiviral Expression Vector

LV011 10 µg
EUR 416.5

pLenti-MCS-EF1-RFP-T2A-puro Lentiviral Expression Vector

LV021 10 µg
EUR 416.5

pAAV-MCS Expression Vector

VPK-410 10 µg
EUR 530

pscAAV-MCS Expression Vector

VPK-430 10 µg
EUR 776.4
Description: Clone your gene of interest into this AAV Expression Vector, then co-transfect along with AAV packaging vectors into a packaging host cell line such as 293AAV.

pLenti-EF1-MCS-PGK-GFP-T2A-PURO Lentiviral Expression Vector

LV211 10 µg
EUR 416.5

pLenti-EF1-MCS-PGK-GFP-T2A-Neo Lentiviral Expression Vector

LV212 10 µg
EUR 416.5

pLenti-EF1-MCS-PGK-RFP-T2A-PURO Lentiviral Expression Vector

LV221 10 µg
EUR 416.5

pLenti-CMV-MCS-EF1α-GFP-T2A-PURO Lentiviral Expression Vector

LV111 10 µg
EUR 416.5

pLenti-CMV-MCS-EF1α-RFP-T2A-PURO Lentiviral Expression Vector

LV121 10 µg
EUR 416.5

pLenti-EF1-MCS-PGK-GFP-T2A-Hygro Lentiviral Expression Vector

LV213 10 µg
EUR 416.5

pLenti-CAG-MCS-PGK-coGFP-T2A-NEO Lentiviral Expression Vector

LV312 10 µg
EUR 416.5

pLenti-CAG-MCS-PGK-coGFP-T2A-HygR Lentiviral Expression Vector

LV313 10 µg
EUR 416.5

pLenti-CAG-MCS-EF1-coGFP-T2A-PURO Lentiviral Expression Vector

LV361 10 µg
EUR 416.5

pLenti-SFFV-MCS-PGK-coGFP-T2A-NEO Lentiviral Expression Vector

LV412 10 µg
EUR 416.5

pLenti-SFFV-MCS-PGK-coGFP-T2A-Puro Lentiviral Expression Vector

LV411 10 µg
EUR 416.5

pLenti-SFFV-MCS-PGK-coGFP-T2A-HygR Lentiviral Expression Vector

LV413 10 µg
EUR 416.5

pLenti-SFFV-MCS-EF1-coGFP-T2A-Puro Lentiviral Expression Vector

LV461 10 µg
EUR 416.5

GCP (green control plasmid for GFP expression)

C15 50 ul
EUR 145
Description: Protein expression

pLenti-CAG-MCS-PGK-TdTomato-T2A-Puro Lentiviral Expression Vector

LV321 10 µg
EUR 416.5

pLenti-CAG-MCS-EF1-TdTomato-T2A-Puro Lentiviral Expression Vector

LV371 10 µg
EUR 416.5

pLenti-SFFV-MCS-PGK-TdTomato-T2A-Puro Lentiviral Expression Vector

LV421 10 µg
EUR 416.5

pLenti-SFFV-MCS-EF1-TdTomato-T2A-Puro Lentiviral Expression Vector

LV471 10 µg
EUR 416.5

baculoCOMPLETE protein expression kit + baculoQUANT all-in-one

400101 5 + 100 reactions
EUR 1419.8

pCDH- CMV- mCherry- EF1- CopGFP- Puro

PVT11078 2 ug
EUR 444

pLenti-MCS Lentiviral Expression Vector

LV000 10 µg
EUR 416.5

pAAV-MCS Promoterless Expression Vector

VPK-411 10 µg
EUR 530

XPack MSCV-XP-GFP-EF1-Puro Expression Lentivirus

XPAK730VA-1 >1 x 10^6 IFUs
EUR 759

XPack MSCV-XP-GFP-EF1-Puro Expression Lentivector

XPAK730PA-1 10 ug
EUR 759

XPack MSCV-XP-Luciferase-EF1-Puro Expression Lentivector

XPAK732PA-1 10 ug
EUR 759

XPack MSCV-XP-Luciferase-EF1-Puro Expression Lentivirus

XPAK732VA-1 >1 x 10^6 IFUs
EUR 759

pLenti-MCS-PGK-PURO Lentiviral Expression Vector

LV001 10 µg
EUR 416.5

pLenti-EF1-MCS-PGK-Neo Lentiviral Expression Vector

LV202 10 µg
EUR 416.5

pLenti-EF1-MCS-PGK-RFP Lentiviral Expression Vector

LV220 10 µg
EUR 416.5

pLenti-CAG-MCS-PGK-NEO Lentiviral Expression Vector

LV302 10 µg
EUR 416.5

pLenti-CAG-MCS- EF1-coGFP Lentiviral Expression Vector

LV360 10 µg
EUR 416.5

pLenti-CMV-MCS-EF1α-RFP Lentiviral Expression Vector

LV120 10 µg
EUR 416.5

pLenti-EF1-MCS-PGK-PURO Lentiviral Expression Vector

LV201 10 µg
EUR 416.5

pLenti-CAG-MCS-PGK-HygR Lentiviral Expression Vector

LV303 10 µg
EUR 416.5

pLenti-CAG-MCS-EF1-PURO Lentiviral Expression Vector

LV351 10 µg
EUR 416.5

pLenti-SFFV-MCS-PGK-NEO Lentiviral Expression Vector

LV402 10 µg
EUR 416.5

pLenti-EF1-MCS-PGK-Hygro Lentiviral Expression Vector

LV203 10 µg
EUR 416.5

pLenti-SFFV-MCS-PGK-Puro Lentiviral Expression Vector

LV401 10 µg
EUR 416.5

pLenti-SFFV-MCS-EF1-Puro Lentiviral Expression Vector

LV451 10 µg
EUR 416.5

pGreen- Puro- pSIH1- H1- copGFP- T2A- Puro

PVT11116 2 ug
EUR 444

pLenti-SFFV-MCS-PGK-Hygro Lentiviral Expression Vector

LV403 10 µg
EUR 416.5

pLenti-CAG-MCS-PGK-TdTomato Lentiviral Expression Vector

LV320 10 µg
EUR 416.5

pLenti-CAG-MCS-EF1-TdTomato Lentiviral Expression Vector

LV370 10 µg
EUR 416.5

XPack MSCV-XP-MCS-EF1-Puro Cloning Lentivector

XPAK710PA-1 10 ug
EUR 730

pLenti-SFFV-MCS-PGK-TdTomato Lentiviral Expression Vector

LV420 10 µg
EUR 416.5

pLenti-SFFV-MCS-EF1-TdTomato Lentiviral Expression Vector

LV470 10 µg
EUR 416.5

pCDH- EF1- MCS- T2A- Puro Plasmid

PVT2335 2 ug
EUR 390

pCDH-CuO-MCS empty cloning lentivector

QM500A-1 10 ug
EUR 534

ACE2 Expression Lentivector, pCDH-CMV-ACE2-EF1α-Puro (Plasmid)

CVD19-100PA-1 10 µg
EUR 728

NRP1 Expression Lentivector, pCDH-CMV-NRP1-EF1α-Neo (Plasmid)

CVD19-140PA-1 10 µg
EUR 728

pMC.CMV-GFP-T2A-Puro-H1-MCS (shRNA expression parental minicircle plasmid)

MNSI505A-1 10 ug
EUR 779

pMC.EF1-GFP-T2A-Puro-H1-MCS (shRNA expression parental minicircle plasmid)

MNSI506A-1 10 ug
EUR 779

FoldHelper-57P. Recombinant baculovirus expressing ERp57 and PDI.

H17 1 ml
EUR 295
Description: Protein expression

pCDH-CMV-MCS-EF1-copGFP-T2A-Puro plasmid

PVT17271 2 ug
EUR 568.8

CNGA2 Expression vector

60642 20 µg
EUR 900
Description: The CNGA2 expression vector is designed to express human cyclic nucleotide-gated cation channel 2 (CNGA2) in mammalian cells.

CNGA2 Expression vector

GWB-PSFA61 20ug Ask for price

pYLEX1 - Expression Vector

FYY203-5MG 5mg Ask for price

pCDH-EF1-MCS*-T2A-GFP

CD526A-1 10 ug
EUR 590

pCDH- CMV- MCS- EF1- turboRFP- T2A- Puro

PVT11077 2 ug
EUR 444

Rac1 Expression Vector Set

STA-454 1 kit
EUR 1765.2
Description: Rac1 Expression Vector Set contains 3 vectors: Rac wild type, T17N dominant negative mutant, and G12V constitutively active mutant.

RhoA Expression Vector Set

STA-456 1 kit
EUR 1765.2
Description: RhoA Expression Vector Set contains 3 vectors: RhoA wild type, T19N dominant negative mutant, and G14V constitutively active mutant.

Cdc42 Expression Vector Set

STA-455 1 kit
EUR 1765.2
Description: Cdc42 Expression Vector Set contains 3 vectors: Cdc42 wild type, T17N dominant negative mutant, and Q61L constitutively active mutant.

H-Ras Expression Vector Set

STA-457 1 kit
EUR 1765.2
Description: H-Ras Expression Vector Set contains 3 vectors: H-Ras wild type, T19N dominant negative mutant, and G12V constitutively active mutant.

pUC57-sgRNA expression vector

PVT18003 2 ug
EUR 309.6

ANPRA/Aequorin Expression vector

60641 20 µg
EUR 900
Description: The ANPRA/Aequorin expression vector is designed to co-express human atrial natriuretic peptide receptor A (ANPRA, also called natriuretic peptide receptor A/guanylate cyclase A) and jellyfish (Aequorea victoria) Aequorin in mammalian cells.

ANPRA/Aequorin Expression vector

GWB-PS0F6A 20ug Ask for price

GFP-Rac1 Expression Vector Set

STA-450 1 kit
EUR 1939.2
Description: GFP-Rac1 Expression Vector Set contains 3 vectors: Rac wild type, T17N dominant negative mutant, and Q61L constitutively active mutant. Each vector also contains a GFP reporter sequence.

GFP-RhoA Expression Vector Set

STA-452 1 kit
EUR 1939.2
Description: GFP-RhoA Expression Vector Set contains 3 vectors: RhoA wild type, T19N dominant negative mutant, and Q63L constitutively active mutant. Each vector also contains a GFP reporter sequence.

GFP-Cdc42 Expression Vector Set

STA-451 1 kit
EUR 1939.2
Description: GFP-Cdc42 Expression Vector Set contains 3 vectors: Cdc42 wild type, T17N dominant negative mutant, and Q61L constitutively active mutant. Each vector also contains a GFP reporter sequence.

Active Rac1 Expression Vector Set

STA-458 1 kit
EUR 1765.2
Description: Active Rac1 Expression Vector Set contains 3 vectors expressing different constitutively active mutants of Rac1: Q61L, Q61L/F37A, and Q61L/Y40C.

ACE2 Expression Lentivector, pCDH-CMV-ACE2-EF1α-Puro (Pre-packaged Lentivirus)

CVD19-100VA-1 >2x10^6 IFUs
EUR 728

NRP1 Expression Lentivector, pCDH-CMV-NRP1-EF1α-Neo (Pre-packaged Lentivirus)

CVD19-140VA-1 >2x10^6 IFUs
EUR 728

pCMV-GFP-LC3 Expression Vector

CBA-401 100 µL
EUR 1243.2
Description: Expression vector contains a fusion of GFP and LC3. A separate GFP control vector is also included.

Lenti-III-HA Expression Vector

LV022 10 μg
EUR 575

Tet-on circRNA Expression Vector

PVT14643 2 ug
EUR 843.6

copGFP-T2A-Puro-pA OmniTag Minicircle Donor

OT501MC-1 10 µg
EUR 709

Lenti-III-UbC Expression Vector

G300 10 μg
EUR 575

Lenti-III-PGK Expression Vector

G305 10 μg
EUR 575

pAAV-IRES-Neo Expression Vector

VPK-416 10 µg
EUR 776.4
Description: Clone your gene of interest into this AAV Expression Vector, then co-transfect along with AAV packaging vectors into a packaging host cell line such as 293AAV.

pAAV-IRES-GFP Expression Vector

VPK-418 10 µg
EUR 530

pAAV-IRES-Bsd Expression Vector

VPK-419 10 µg
EUR 776.4
Description: Clone your gene of interest into this AAV Expression Vector, then co-transfect along with AAV packaging vectors into a packaging host cell line such as 293AAV.

pAAV-IRES-Puro Expression Vector

VPK-415 10 µg
EUR 776.4
Description: Clone your gene of interest into this AAV Expression Vector, then co-transfect along with AAV packaging vectors into a packaging host cell line such as 293AAV.

pAAV-IRES-Hygro Expression Vector

VPK-417 10 µg
EUR 776.4
Description: Clone your gene of interest into this AAV Expression Vector, then co-transfect along with AAV packaging vectors into a packaging host cell line such as 293AAV.

Active H-Ras Expression Vector Set

STA-459 1 kit
EUR 1765.2
Description: Active H-Ras Expression Vector Set contains 3 vectors expressing different constitutively active mutants of H-Ras: V12, V12S35, and V12C40.

pSMPUW-Neo Lentiviral Expression Vector

VPK-213 10 µg
EUR 505

pSMPUW-Puro Lentiviral Expression Vector

VPK-212 10 µg
EUR 505

pCDH-EF1-Luc-T2A-copGFP

PVT17649 2 ug
EUR 508.8

pSMPUW-Hygro Lentiviral Expression Vector

VPK-214 10 µg
EUR 505

pCDH-CMV-MCS-EF1-copGFP+Puro cDNA Clon/Exp Vector [pre-packaged]

CD513VB-1 >1 x 10^6 IFUs
EUR 720

Baculovirus expression vector pAc-g-CH3

30R-AB001 5 ug
EUR 685
Description: Baculovirus cassette vector pAc-l-CH3 for the expression of human, humanized or chimeric IgG(lambda) in insect cells and secretion of assembled antibodies into the supernatant.

Baculovirus expression vector pAc-g-CH3

GWB-EC6621 0.01 ml Ask for price

pCDH-CMV-MCS-EF1-copGFP cDNA Clon/Exp Vector [pre-packaged virus]

CD511VB-1 >1 x 10^6 IFUs
EUR 720

Exoenzyme C3 (Rho Inhibitor) Expression Vector

STA-460 1 kit
EUR 860.4
Description: This mammalian expression vector codes for Exoenzyme C3, a Rho inhibitor.

pSMPUW-GFP-LC3 Lentiviral Expression Vector

LTV-801 10 µg
EUR 1444.8
Description: Expression vector contains a fusion of GFP and LC3. A separate GFP control vector is also included.

pSMPUW-IRES-Neo Lentiviral Expression Vector

VPK-216 10 µg
EUR 505

pSMPUW-IRES-Puro Lentiviral Expression Vector

VPK-215 10 µg
EUR 505

pSMPUW-IRES-Hygro Lentiviral Expression Vector

VPK-217 10 µg
EUR 505

Mouse IL-23 Enhanced Episomal Expression Vector

EEV651A-1 100 ug
EUR 812

GC (green control baculovirus expressing GFP)

C14 1 ml
EUR 195
Description: Protein expression

pMXs-miRNA-GFP/Puro Retroviral Expression Vector

RTV-017 10 ?g
EUR 505

BV-p53. Recombinant baculovirus expressing p53 (wt).

BV53 1 ml
EUR 980
Description: Drug discovery, Transcription factors, baculovirus

pSMPUW-IRES-Blasticidin Lentiviral Expression Vector

VPK-219 10 µg
EUR 505

BV-SOD1. Recombinant baculovirus expressing SOD1.

PD25 1 ml
EUR 899
Description: Drug discovery, Protein folding diseases, baculovirus

pSMPUW Universal Lentiviral Expression Vector (Promoterless)

VPK-211 10 µg
EUR 505

BV-Tau412. Recombinant baculovirus expressing 412 aa Tau isoform.

PD13 1 ml
EUR 899
Description: Drug discovery, Protein folding diseases, baculovirus

BV-Tau352. Recombinant baculovirus expressing 352 aa Tau isoform.

PD3 1 ml
EUR 899
Description: Drug discovery, Protein folding diseases, baculovirus

BV-Tau383. Recombinant baculovirus expressing 383 aa Tau isoform.

PD7 1 ml
EUR 899
Description: Drug discovery, Protein folding diseases, baculovirus

BV-Tau381. Recombinant baculovirus expressing 381 aa Tau isoform.

PD9 1 ml
EUR 899
Description: Drug discovery, Protein folding diseases, baculovirus

pCDH-CuO-MCS-T2A-GFP co-inducible T2A lentivector

QM521A-1 10 ug
EUR 616

pCDH-CuO-MCS-T2A-RFP co-inducible T2A lentivector

QM522A-1 10 ug
EUR 616

FoldHelper-37. Recombinant baculovirus expressing cdc37.

H18 1 ml
EUR 395
Description: Protein expression

Excision only piggyBac Transposase expression vector, 50 rxns

PB220PA-1 10 ug
EUR 471

pMC.CMV-GFP-H1-MCS (shRNA expression parental minicircle plasmid)

MNSI500A-1 10 ug
EUR 779

BV-SOD1-GFP. Recombinant baculovirus expressing SOD1-GFP fusion.

PD29 1 ml
EUR 899
Description: Drug discovery, Protein folding diseases, baculovirus

SARS-CoV-2 Spike Glycoprotein Expression (S) Lentivector, pCDH-CMV-SARS-CoV-2-S-EF1α-Puro (Plasmid)

CVD19-130PA-1 10 µg
EUR 728

BV-DRD1. Recombinant baculovirus expressing Dopamine receptor 1 (DRD1).

GD3 1 ml
EUR 499
Description: Drug discovery, GPCRs, baculovirus

After 58 days, ferumoxytol could be detected in HFBSCs in parts of the brain tissue. These results indicate that HFBSCs able to survive after transplantation of the brain and suggest that these cells may undergo differentiation towards neural cell lineages, which support the potential use for cell-based therapy for TBI.